# I was quoting the statistics, I wasn't pretending to be a statisitcian

Sir Roy Meadow struck off by GMC

BBC News, 15 July 2005

Beyond reasonable doubt

Plus Magazine, 2002

Helen Joyce

Multiple sudden infant deaths--coincidence or beyond coincidence

Paediatric and Perinatal Epidemiology 2004, 18, 320-326

Roy Hill

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Sir Roy Meadow is a pediatrician well known for his research in child abuse. The BBC article reports that the UK General Medical Council (GMC) has found Sir Roy guilty of serious professional misconduct has "struck him off" the medical registry. If upheld under appeal, this will prevent Meadow from practicing medicine in the UK.

This decision was based on flawed statistical estimate that Meadow made while testifying as an expert witness in a 1999 trial in which a Sally Clark was found guilty of murdering her two baby boys and given a life sentence.

To understand his testimony we need to know what a cot death is. This is another name for SIDS (sudden infant death syndrome).

The name SIDS was proposed by the pathologist Bruce Beckwih at a conference in 1969 and the definition, which is still current, was formulated at the conference by Beckwith and others as follows:

The sudden death of a baby that is unexpected by history and in whom a

thorough post-mortem examination fails to demonstrate an adequate cause of death.

The the death of Sally Clark's baby was reported as a cot death. Then when the second baby died Sally Clark was accused of murdering both her children.

We were not able to find a transcript for the original trial but we were able from Lexis Nexis (1) to find transcripts of two appeals that the Clarks made, one in October 2000 that they lost, and the other in 2003 which they won and Sally Clark was released from jail. The 2003 transcript reported on the statistical testimony in the original trial as follows:

Professor Meadow was asked about some statistical information as to the happening of two cot deaths within the same family, which at that time was about to be published in a report of a government funded multi--disciplinary research team, the Confidential Enquiry into Sudden Death in Infancy (CESDI) entitled 'Sudden Unexpected Deaths in Infancy' to which the professor was then writing a Preface. Professor Meadow said that it was 'the most reliable study and easily the largest and in that sense the latest and the best' ever done in this country.

It was explained to the jury that there were factors that were suggested as relevant to the chances of a SIDS death within a given family; namely the age of the mother, whether there was a smoker in the houshold and the absence of a wage-earner in the family.

None of these factors had relevance to the Clark family and Professor Meadow was asked if a figure of 1 in 8,543 reflected the risk of there being a single SIDS within such a family. He agreed that it was. A table from the CESDI report was placed before the jury. He was then asked if the report calculated the risk of two infants dying of SIDS in that family by chance. His reply was: 'Yes, you have to multiply 1 in 8,543 times 1 in 8,543 and I think it gives that in the penultimate paragraph. It points out that it's approximately a chance of 1 in 73 million.'

It seems that at this point Professor Meadow's voice was dropping and so the figure was repeated and then Professor Meadow added: 'In England, Wales and Scotland there are about say 700,000 live births a year, so it is saying by chance that happening will occur about once every hundred years.'

Mr Spencer [Prosecutor] then pointed to the suspicious features alleged by the Crown in this present case and asked: 'So is this right, not only would the chance be 1 in 73 million but in addition in these two deaths there are features which would be regarded as suspicious in any event?' He elicited the reply 'I believe so'.

All of this evidence was given without objection from the defence but Mr Bevan QC (who represented the appellant at trial and at the first appeal but not before us) cross--examined the doctor. He put to him figures from other research that suggested that the figure of 1 in 8,543 for a single cot death might be much too high. He then dealt with the chance of two cot deaths and Professor Meadow responded: 'This is why you take what's happened to all the children into account, and that is why you end up saying the chance of the children dying naturally in these circumstances is very, very long odds indeed one in 73 million.' He then added:

'. . . it's the chance of backing that long odds outsider at the Grand National, you know; let's say it's a 80 to 1 chance, you back the winner last year, then the next year there's another horse at 80 to 1 and it is still 80 to 1 and you back it again and it wins. Now here we're in a situation that, you know, to get to these odds of 73 million you've got to back that 1 in 80 chance four years running, so yes, you might be very, very lucky because each time it's just been a 1 in 80 chance and you know, you've happened to have won it, but the chance of it happening four years running we all know is extraordinarily unlikely. So it's the same with these deaths. You have to say two unlikely events have happened and together it's very, very, very unlikely.'

The trial judge clearly tried to divert the jury away from reliance on this statistical evidence. He said: 'I should, I think, members of the jury just sound a word of caution about the statistics. However compelling you may find them to be, we do not convict people in these courts on statistics. It would be a terrible day if that were so. If there is one SIDS death in a family, it does not mean that there cannot be another one in the same family.'

Note that Meadow did obtain the odds of 73 million to one from the CESDI so there is some truth to the statement "I was quoting the statistics, I wan't retending to be a statisician" that Meadow made to the

There are three obvious problems with this 1 in 73 million statistic: (1) Because of environmental and genetics effects it seems very unlikely that the a SIDS death for a families the first baby and for their second baby are independent and (2) giving such odds with no further explanation might suggest to the jury that their is a 1 in 74 million chance that Sally Clark is innocent and (3) neither the defense or the prosecution suggested that the deaths were SIDS deaths--the prosecution claiming that they were murders, and the defense that they were natural deaths explained by the medical evidence. As far as we can tell only problem (1) was seriously discussed in the news. The first article to discuss this issue appears to be the article "False statistics may have led to solicitor's murder conviction" by Sherry Norton in The Independent (London), December 31, 1999. This article reports on and article by Dr Stephen Watkins, director of public health at Stockport health entitled "Conviction by mathematical error? (BMJ, 2000, 320, 2-3). Norton writes:

In Britain, there are 344 cot deaths each year, with the risk for the whole population being one cot death in 2.75 million. There are 378,000 second or subsequent births in England each year, and Dr Watkins has calculated that, if cot death is random, two such deaths will occur in the same family somewhere in England once every seven years.

However, because cot deaths are not random and can be linked to genetic defects, social class and lifestyle, recurrence rates have been found to be about five times the general rate. Therefore Dr Watkins has concluded that two cot deaths in the same family will, on average, occur at least once every one and a half years.

Problem (2) was addressed by Wai-Chin Leung, Senior Registrar in Public Health Medicine in his response to Watkins article: "Conditional probability should be applied" to Watkins's article. Wai-Ching writes:

It is vital to state the precise conditional and outcome events as well as the underlying assumptions in quoting probability figures. All the figures quoted by Watkins(1) in his discussion about the use of probability in the conviction of Sally Clark could be correct:-

1) The probability that two consecutive infants died of cot death in a given social class I family is 1 in 73 million, assuming no increase in recurrence rate.

2) The probability that two consecutive infants died of cot death in a given social class I family, given that the first infant had already died, is 1 in 8,500, again assuming no increase in recurrence rate.

3) The probability that two consecutive infants died of cot death in a family is 1 in 2.75 million, again assuming no increase in recurrence rate.

However, none of these are relevant to the jury. The relevant question is: What is the probability that the causes of deaths of the infants in this family were cot deaths, given that these deaths have occurred? Surely, the answer would depend on the comparative likelihood of the two possible causes of death - cot death and homicide. For example, if we can rule out homicide completely (e.g. by several other witnesses), the probability that the causes were cot death is 1 (certainty).

Thus Wai-Ching is talking about the "Prosecutor's Paradox." This is usually analyzed using Bayes Theorem which is probably too much for the jury. However, as he points out, there is a much simpler way to explain this. We need only estimate the probability that the deaths are murders given that are murders or SIDS deaths. We shall see later that one estimate shows that deaths are 9 times more likely than cot deaths. Thus with no other information, if the deaths are cot deaths or murders the probability that Sally Clark is innocent is 9/10 and faced with this situation the jury would certainly not convict Sally Clark. This may not be so convincing if we compared murders with any natural deaths but it would probably still say that murder was more likely that natural death.

These were nicely spelled out by a letter from the Royal Statistical Society to the Lord Chanceller dated 23 January 2002. This letter included the following discussion of the statistical issues involved:

You will be aware of the considerable public attention aroused by the recent conviction, confirmed on appeal, of Sally Clark for the murder of her two infants. One focus of the public attention was the statistical evidence given by a medical expert witness, who drew on a published study to obtain an estimate of the frequency of sudden infant death syndrome (SIDS, or "cot death") in families having some of the characteristics of the defendant's family. The witness went on to square this estimate to obtain a value of 1 in 73 million for the frequency of two cases of SIDS in such a family. This figure had an immediate and dramatic impact on all media reports of the trial, and it is difficult to believe that it did not also influence jurors.

The calculation leading to 1 in 73 million is invalid. It would only be valid if SIDS cases arose independently within families, an assumption that would need to be justified empirically. Not only was no such empirical justification provided in the case, but there are very strong reasons for supposing that the assumption is false. There may well be unknown genetic or environmental factors that predispose families to SIDS, so that a second case within the family becomes much more likely than would be a case in another, apparently similar, family.

A separate concern is that the characteristics used to classify the Clark family were chosen on the basis of the same data as was used to evaluate the frequency for that classification. This double use of data is well recognize by statisticians as perilous, since it can lead to subtle yet important biases.

For these reasons, the 1 in 73 million figure cannot be regarded as statistically valid. The Court of Appeal recognized flaws in its calculation, but seemed to accept it as establishing "... a very broad point, namely the rarity of double SIDS" [AC judgment, para 138]. However, not only is the error in the 1 in 73 million figure likely to be very large, it is almost certainly in one particular direction - against the defendant. Moreover, following from the 1 in 73 million figure at the original trial, the expert used a figure of about 700,000 UK births per year to conclude that "... by chance that happening will occur every 100 years". This conclusion is fallacious, not only because of the invalidity of the 1 in 73 million figure, but also because the 1 in 73 million figure relates only to families having some characteristics matching that of the defendant. This error seems not to have been recognized by the Appeal Court, who cited it without critical comment [AC judgment para 115]. Leaving aside the matter of validity, figures such as the 1 in 73 million are very easily misinterpreted. Some press reports at the time stated that this was the chance that the deaths of Sally Clark's two children were accidental. This mis-interpretation is a serious error of logic known as the Prosecutor's Fallacy (1). The jury needs to weigh up two competing explanations for the babies' deaths: SIDS or murder. The fact that two deaths by SIDS are quite unlikely is, taken alone, of little value. Two deaths by murder may well be even more unlikely. What matters is the relative likelihood of the deaths under each explanation, not just how unlikely they are under one explanation.

References

Transcriipt for the 2000 and 2003 appeals can be obtained from Lexis Nexis following the following route:

Open Lexis Nexis

Choose "Legal Research" from the sidebar

From "Case Law" choose "Get a Case"

Choose" Commonwealth and Foreign Nations" from the sidebar

Choose "Sally Clark" for the " Keyword"

Choose "UK Cases" for the "Source"

Choose "Previous five years" for the "Date."

The two " r v Clarks" are the appeals.

To be continued